The VIVA-MIND Clinical Trial is Designed Especially for Early AD

The VIVA-MIND trial is designed to determine if the study drug, varoglutamstat, can stabilize or slow memory and thinking problems that increase in early AD.
In early AD, a specific and toxic form of the amyloid protein accumulates in the brain. This toxic protein, called N3pE, appears to damage brain cells and surrounding tissues, and activates a strong inflammatory response.
The amyloid protein N3pE is not found in healthy individuals and increases with AD progression. VIVA-MIND researchers suspect that N3pE may play a major role in the decline of memory and thinking skills in early AD.
While many older adults feel as though their memory isn’t as good as it used to be, there are distinct differences between normal cognitive aging and the decline observed in people on the AD trajectory. People with early AD experience measurable decline in memory, verbal ability, decision making, and judgement.